KMID : 0363220150530100766
|
|
Korean Journal of Dermatology 2015 Volume.53 No. 10 p.766 ~ p.772
|
|
The Therapeutic Effect of 1% Sodium Tetradecyl Sulfate Sclerotherapy of Pyogenic Granuloma
|
|
Chae Soo-Yuhl
Sim Hyun-Bo Jang Yong-Hyun Lee Weon-Ju Kim Do-Won Lee Seok-Jong
|
|
Abstract
|
|
|
Background: For the treatment of pyogenic granuloma (PG), surgical excision, electrocautery, and laser therapy have been employed, apart from other methods. Sodium tetradecyl sulfate (STS) sclerotherapy, as a minimally invasive treatment for vascular lesion, is frequently used for vascular malformations with considerable efficacy and safety. However, there have been a few reports about its use in the treatment of PG.
Objective: This study was conducted to evaluate the efficacy, recurrence, and side effects of sclerotherapy using 1% STS in the treatment of PG.
Methods: We evaluated 72 patients with PG who were treated with 1% STS from January 2008 to December 2014. Sclerotherapy using 1% STS was performed by ¡°blind¡± intralesional injection without the aid of imaging such as ultrasonography. The results were evaluated by physical examination, photographic evaluation, and the patient`s subjective satisfaction, and then they were classified into 3 groups: complete remission, partial remission, and no change. Recurrence and side effects were also evaluated.
Results: Complete remission of PG was achieved in 65 (90.3%) of patients after 1.23 average sessions (range, 1¡5 sessions). The remaining patients showed partial remission, with no instances of the treatment resulting in no change. One case of recurrence (1.4%) from partial remission group was seen after 3 months. Clinically, side effects such as pain, tenderness, hyperpigmentation, ulcer, numbness, scarring, and hair loss patches were noted in 18 (25%) patients, but these were all mild and transient.
Conclusion: 1% STS sclerotherapy can be recommended as an effective therapeutic modality for the treatment of PG with insignificant adverse effects and low recurrence rate.
|
|
KEYWORD
|
|
Pyogenic granuloma, Sclerotherapy, Sodium tetradecyl sulfate
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|